D. Huber, D. A. Gutnisky, S. Peron, D. H. O’Connor, J. S. Wiegert, L. Tian, T. G. Oertner, L. L. Looger & K. Svoboda
Summary
- Chronic calcium imaging in learning behavior paradigm.
- Dynamic plastically change during learning in single neuron.
- Good model fitting using machine learning algorithm.
Comments
This paper have technical impact rather than scientific impact (chronic imaging).
This team have very high imaging (and behavior task under microscopy) techniques and improve it very very high speed.
About this paper, first, I surprised the speed of learning.
The mice learn the task within at least 3 sessions (200-400 trials per session, maybe 1 session per day) !
If the reason of this high speed learning is whisker related task, I become very very happy ^m^
I wondered why licking related behaviors code in vibrissa primary moter (vM1) area?
I thought "is that mean there may be no specific region for some body parts in M1 area? "
I want to catch up to this team in technical level as fast as possible.
